Abstract Background The c-Jun N-terminal kinase (JNK) pathway is an evolutionarily conserved regulator of cell death, which is essential for coordinating tissue homeostasis.In this study, we have characterized the Drosophila Ste20-like kinase Slik as a novel modulator Cuticle Cream of JNK pathway-mediated apoptotic cell death.Results First, ectopic
Abstract Background Lifelong production of the many types of mature blood cells from less differentiated progenitors is a WOMENS JUMPERS hierarchically ordered process that spans multiple cell divisions.The nature and timing of the molecular events required to integrate the environmental signals, transcription factor activity, epigenetic modificati
Paranoplocephala etholeni n.sp., parasitizing the meadow vole Microtus lower board pennsylvanicus in Alaska and Wisconsin, USA is described.Paranoplocephala etholeni is morphologically most closely related to the Nearctic Paranoplocephala ondatrae (Rausch, 1948).Available data suggest that P.etholeni is a host-specific, locally rare species that ma
Medicine in the 21 st century is increasingly dependent on technology.Unlike in many other areas, the cost of medical technology is not declining and its increasing use contributes to the spiraling healthcare costs.Many medical professionals equate progress in medicine to increasing use of sophisticated technology that is often expensive and beyond